2019年5月13日，来自加拿大Rogue Research Inc.公司的高级工程师在中科院心理所安装了中国首套（全球第六套）脉冲参数可控的经颅磁刺激器（cTMS）。cTMS的发明是对TMS技术革命性突破！cTMS可以自由控制脉冲波形!!!
cTMS （ controllable pulse parameter transcranial magnetic stimulation）的推出是对TMS技术的重大突破和改变。cTMS带来的新的刺激脉冲波形和参数，可以显著提高刺激调控的效果。这一技术目前刚刚正式上市，为助力科研提高了全新的工具。
cTMS 优势之一是能够产生新的 TMS 脉冲种类。文献中描述 cTMS 设备已有几年，它的设计是基于 Angel Peterchev 博士在杜克大学的创新工作。他在研究中引入了大量术语，一些相关的参考文献请见本页的最后部分。
Selected publications featuring cTMS
Brain Stimul. 2016 Jan-Feb;9(1):39-47. doi: 10.1016/j.brs.2015.08.013. Epub 2015 Sep 1.
Enhancement of Neuromodulation with Novel Pulse Shapes Generated by Controllable Pulse Parameter Transcranial Magnetic Stimulation.
Goetz SM1, Luber B2, Lisanby SH2, Murphy DL1, Kozyrkov IC1, Grill WM3, Peterchev AV4.
Clin Neurophysiol, 127(1), 675-83 (2015)
Effect of coil orientation on strength-duration time constant and I-wave activation with controllable pulse parameter transcranial magnetic stimulation.
D’Ostilio K, Goetz SM, Hannah R, Ciocca M, Chieffo R, Chen JC, Peterchev AV, Rothwell JC
Clin Neurophysiol. 2016 Jan;127(1):675-83. doi: 10.1016/j.clinph.2015.05.017. Epub 2015 May 30.
Effect of coil orientation on strength-duration time constant and I-wave activation with controllable pulse parameter transcranial magnetic stimulation.
D’Ostilio K1, Goetz SM2, Hannah R3, Ciocca M4, Chieffo R5, Chen JC6, Peterchev AV7, Rothwell JC3.
J Neural Eng. 2014 Oct;11(5):056023. doi: 10.1088/1741-2560/11/5/056023. Epub 2014 Sep 22.
Controllable pulse parameter transcranial magnetic stimulator with enhanced circuit topology and pulse shaping.
Peterchev AV1, DʼOstilio K, Rothwell JC, Murphy DL.
Clin Neurophysiol. 2013 Jul;124(7):1364-72. doi: 10.1016/j.clinph.2013.01.011. Epub 2013 Feb 20.
Pulse width dependence of motor threshold and input-output curve characterized with controllable pulse parameter transcranial magnetic stimulation.
Peterchev AV1, Goetz SM, Westin GG, Luber B, Lisanby SH.
J Neural Eng. 2011 Jun;8(3):036016. doi: 10.1088/1741-2560/8/3/036016. Epub 2011 May 4.
Repetitive transcranial magnetic stimulator with controllable pulse parameters.
Peterchev AV1, Murphy DL, Lisanby SH.
Conf Proc IEEE Eng Med Biol Soc. 2010;2010:2922-6. doi: 10.1109/IEMBS.2010.5626287.
Repetitive transcranial magnetic stimulator with controllable pulse parameters (cTMS).
Peterchev AV1, Murphy DL, Lisanby SH.
IEEE Trans Biomed Eng. 2008 Jan;55(1):257-66. doi: 10.1109/TBME.2007.900540.
A transcranial magnetic stimulator inducing near-rectangular pulses with controllable pulse width (cTMS).
Peterchev AV1, Jalinous R, Lisanby SH.
JOURNAL OF NEURAL ENGINEERING, 11 (5), doi:10.1088/1741-2560/11/5/056023
Controllable pulse parameter transcranial magnetic stimulator with enhanced circuit topology and pulse shaping.
Peterchev, A.V., D’Ostilio, K., Rothwell, J.C., Murphy, D.L. (2014).
Abstracts in conferences:
Hannah R, D’Ostilio K, Goetz S, Ciocca M, Chieffo R, Chen J-CA, Peterchev AV, Rothwell JC (2015)
Effects of transcranial magnetic stimulation coil orientation and pulse width on short-latency afferent inhibition.
Brain Stim 8, 379-380
Hannah R, Ciocca M, Sommer M, Hammond P, Rothwell J (2014)
Continuous theta burst stimulation with monophasic pulses: effect of current direction.
Clin Neurophysiol 125, S1–S339
Sommer M, Ciocca M, Hannah R, Hammond P, Neef N, Paulus W, Rothwell JC (2014)
Intermittent theta burst stimulation inhibits human motor cortex when applied with mostly monophasic (anterior-posterior) pulses.
Clin Neurophysiol 125, S1–S339
